Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6459095 | 1.00 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2A6 | |
| SCHEMBL6461267 | 0.86 | KDM1A (0.43) | SLC6A2SLC6A4SLC6A3TSHRL3MBTL1 | |
| SCHEMBL6461265 | 0.86 | KDM1A (0.43) | SLC6A2SLC6A4SLC6A3TSHRL3MBTL1 | |
| SCHEMBL11140195 | 0.85 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2A6 | |
| SCHEMBL11140216 | 0.85 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3CYP1A2CYP2A6 | |
| SCHEMBL6460483 | 0.84 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6460293 | 0.84 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3L3MBTL1KDM1A | |
| SCHEMBL6460298 | 0.84 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3L3MBTL1KDM1A | |
| SCHEMBL6460474 | 0.84 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6464612 | 0.83 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3FDFT1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |