Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464627 | 1.00 | KDM1A (0.33) | KDM1ATAS1R3TAS1R1TAS1R2AR | |
| SCHEMBL6453673 | 0.85 | RXRA (0.31) | KDM1A | |
| SCHEMBL6453669 | 0.85 | RXRA (0.31) | KDM1A | |
| SCHEMBL6452497 | 0.83 | KDM1A (0.35) | KDM1ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6452489 | 0.83 | KDM1A (0.35) | KDM1ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6453222 | 0.83 | CYP2C9 (0.30) | — | |
| SCHEMBL6453225 | 0.83 | CYP2C9 (0.30) | — | |
| SCHEMBL6454111 | 0.82 | — | — | |
| SCHEMBL6454107 | 0.82 | — | — | |
| SCHEMBL6462675 | 0.82 | HCRTR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |