Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464668 | 1.00 | KDM1A (0.38) | KDM1AMAOAMAOBDRD2GRIN2B | |
| SCHEMBL6464677 | 1.00 | KDM1A (0.38) | KDM1AMAOAMAOBDRD2GRIN2B | |
| SCHEMBL15274898 | 0.85 | DRD2 (0.46) | KDM1AMAOAMAOBDRD2DDB1 | |
| SCHEMBL6451918 | 0.84 | KDM1A (0.39) | KDM1AMAOAMAOBDRD2GRIN2B | |
| SCHEMBL6451194 | 0.84 | KDM1A (0.39) | KDM1AMAOAMAOBDRD2GRIN2B | |
| SCHEMBL6451193 | 0.84 | KDM1A (0.39) | KDM1AMAOAMAOBDRD2GRIN2B | |
| SCHEMBL6451917 | 0.84 | KDM1A (0.39) | KDM1AMAOAMAOBDRD2GRIN2B | |
| SCHEMBL6464028 | 0.84 | HRH3 (0.37) | KDM1ASLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL6455658 | 0.84 | IDO1 (0.35) | ALDH1A1LMNA | |
| SCHEMBL6455657 | 0.84 | IDO1 (0.35) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |