Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 16/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 16/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5133204 | 0.87 | TAS1R3 (0.50) | TAS1R3TAS1R1CHRM1AKR1A1CHRM3 | |
| SCHEMBL17141303 | 0.87 | DPP7 (0.42) | TAS1R3TAS1R1DPP7PLA2G2C | |
| SCHEMBL28960765 | 0.86 | CYP2D6 (0.37) | TAS1R3TAS1R1ADRA1ATDP1CYP2D6 | |
| SCHEMBL28355266 | 0.85 | PLA2G2C (0.47) | DPP7PLA2G2C | |
| SCHEMBL6120544 | 0.79 | TAS1R3 (0.44) | TAS1R3TAS1R1CHRM1AKR1A1CHRM3 | |
| SCHEMBL18063334 | 0.79 | CYP2D6 (0.33) | CYP2D6CYP2C19 | |
| SCHEMBL20914941 | 0.79 | PLA2G2C (0.51) | TAS1R3TAS1R1CHRM1AKR1A1CHRM3 | |
| SCHEMBL17112231 | 0.79 | CYP2D6 (0.33) | CYP2D6CYP2C19 | |
| SCHEMBL6717845 | 0.79 | TAS1R3 (0.50) | TAS1R3TAS1R1CHRM1AKR1A1CHRM3 | |
| SCHEMBL28681574 | 0.78 | PLA2G10 (0.50) | TAS1R3TAS1R1CHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515702-A1 | ABUSE-PROTECTED ADMINISTRATION FORM | Grünenthal GmbH (DE) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003105808-A1 | ABUSE-PROTECTED ADMINISTRATION FORM | Grünenthal GmbH (DE) | 2003-12-24 | — | — | WO | disclosed |