Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 4/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5988255 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2LMNATRPA1KDM4E | |
| SCHEMBL943149 | 0.81 | GABRA1 (0.54) | GABRA1GABRB2MMP1MDM4TP53 | |
| SCHEMBL9546806 | 0.79 | GABRA1 (0.46) | GABRA1GABRB2LMNATRPA1KDM4E | |
| SCHEMBL1129263 | 0.77 | CYP2D6 (0.41) | GABRA1GABRB2LMNATRPA1 | |
| SCHEMBL26503628 | 0.77 | TAAR1 (0.45) | GABRA1GABRB2KDM4EALDH1A1 | |
| SCHEMBL28052525 | 0.77 | GABRA1 (0.40) | GABRA1GABRB2LMNATRPA1KDM4E | |
| SCHEMBL15319485 | 0.77 | TAAR1 (0.45) | GABRA1GABRB2KDM4EALDH1A1 | |
| SCHEMBL13692275 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2LMNATRPA1ALDH1A1 | |
| SCHEMBL3672930 | 0.77 | SLC6A2 (0.52) | — | |
| SCHEMBL3459705 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2LMNATRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050042676-A1 | Characterising polypeptides | ELECTROPHORETICS LIMITED (GB) | 2005-02-24 | — | — | US | disclosed |
| EP-1397505-A2 | CHARACTERISING POLYPEPTIDES | Xzillion GmbH & CO.KG (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-1267170-A1 | Method for characterising polypeptides | Xzillion GmbH & CO.KG (DE) | 2002-12-18 | — | — | EP | disclosed |
| WO-2002099124-A2 | CHARACTERISING POLYPEPTIDES | XZILLION GMBH & CO. KG (DE) | 2002-12-12 | — | — | WO | disclosed |