SCHEMBL6465059

SCHEMBL6465059

Cc1ccc(S(=O)(=O)N(C(N)=O)c2cccc(N(C(N)=O)S(=O)(=O)c3ccc(C)cc3)c2C)cc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 3/20 0.54
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
LMNA P02545 5/20 0.48
TSHR P16473 1/20 0.48
KDM4E B2RXH2 1/20 0.46
TP53 P04637 3/20 0.43
MAPT P10636 2/20 0.43
KEAP1 Q14145 2/20 0.43
NFE2L2 Q16236 2/20 0.43
ALDH1A1 P00352 1/20 0.42
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
HPGD P15428 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6243114 0.89 C5AR1 (0.53) C5AR1MEN1KMT2ALMNATSHR
SCHEMBL6243974 0.87 C5AR1 (0.50) C5AR1MEN1KMT2ALMNATSHR
SCHEMBL6326490 0.86 C5AR1 (0.53) C5AR1MEN1KMT2ALMNATSHR
SCHEMBL6244269 0.84 C5AR1 (0.50) C5AR1MEN1KMT2ALMNATSHR
SCHEMBL7613742 0.82 C5AR1 (0.49) C5AR1MEN1KMT2ALMNATSHR
SCHEMBL6241748 0.81 LMNA (0.55) C5AR1MEN1KMT2ALMNAKDM4E
SCHEMBL27991408 0.80 LMNA (0.62) MEN1KMT2ALMNAKDM4ETP53
SCHEMBL6243993 0.80 LMNA (0.62) MEN1KMT2ALMNAKDM4ETP53
SCHEMBL1878018 0.79 CA12 (0.58) C5AR1MEN1KMT2ALMNAKDM4E
SCHEMBL28082162 0.79 C5AR1 (0.46) C5AR1MEN1KMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
US-5851951-A Heat sensitive recording material OJI PAPER CO., LTD. (JP) 1998-12-22 US disclosed
EP-0792754-A2 Heat sensitive recording material Oji Paper Co., Ltd. (JP) 1997-09-03 EP disclosed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US disclosed