Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.60 |
| ▸ | PGR | P06401 | 10/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.47 |
| ▸ | SHBG | P04278 | 2/20 | 0.46 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466234 | 0.86 | ALDH1A1 (0.56) | ARPGRSHBGSERPINA6SLC22A1 | |
| SCHEMBL6466916 | 0.84 | AR (0.59) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL6466919 | 0.84 | AR (0.59) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL6462161 | 0.83 | AR (0.74) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL5017880 | 0.80 | AR (0.66) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL7879965 | 0.80 | AR (0.66) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL6464801 | 0.80 | AR (0.66) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL6468738 | 0.78 | AR (0.60) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL5017844 | 0.77 | AR (0.68) | ARPGRNR3C2SHBGSERPINA6 | |
| SCHEMBL13216966 | 0.77 | AR (0.71) | ARPGRNR3C2SHBGSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881728-B1 | 14-β, 17-α-hydroxymethylandrostane derivatives as androgens | AKZO NOBEL N.V. (NL) | 2005-04-19 | — | — | US | disclosed |
| EP-1163259-B1 | 14.BETA.,17-ALPHA-HYDROXYMETHYLANDROSTANE DERIVATIVES AS ANDROGENS | AKZO NOBEL NV (NL) | 2002-11-20 | — | — | EP | disclosed |