Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.42 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6930413 | 0.99 | MCHR1 (0.52) | MCHR1KDM4ELMNASMN1; SMN2MAPKAPK2 | |
| Hydrochloric Acid SCHEMBL6459228 | 0.99 | MCHR1 (0.52) | MCHR1KDM4ELMNASMN1; SMN2MAPKAPK2 | |
| SCHEMBL6455735 | 0.87 | MCHR1 (0.53) | MCHR1KDM4ELMNASMN1; SMN2CLK4 | |
| SCHEMBL6464399 | 0.86 | MCHR1 (0.52) | MCHR1KDM4ELMNASMN1; SMN2CLK4 | |
| SCHEMBL6464657 | 0.86 | MCHR1 (0.53) | MCHR1KDM4ELMNASMN1; SMN2CLK4 | |
| SCHEMBL5780729 | 0.85 | MCHR1 (0.62) | MCHR1KDM4ELMNASMN1; SMN2CDC7 | |
| SCHEMBL6874577 | 0.84 | LMNA (0.52) | MCHR1KDM4ELMNASMN1; SMN2MAPK1 | |
| SCHEMBL6874583 | 0.84 | LMNA (0.52) | MCHR1KDM4ELMNASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL6459226 | 0.83 | MCHR1 (0.48) | MCHR1KDM4ELMNASMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL6459221 | 0.83 | MCHR1 (0.48) | MCHR1KDM4ELMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | TAISHO PHARMACEUTICAL CO., LTD. | 2005-09-08 | — | — | US | disclosed |
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | HCRTR2, MCHR1, MCHR2 | MCHR1 2/4885KDM4E 1190/4885LMNA 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.