SCHEMBL6465632

SCHEMBL6465632

Cc1cc2c(cc1Cl)oc1c(Cl)cc(Cl)c(Cl)c12

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AHR P35869 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10419701 0.85 AHR (1.00) AHR
SCHEMBL6466427 0.77 AHR (0.76) AHR
SCHEMBL2285594 0.74 AHR (1.00) AHR
SCHEMBL3885056 0.72 AHR (0.67) AHR
SCHEMBL6388502 0.71 AHR (0.67) AHR
SCHEMBL6466778 0.71 AHR (0.73) AHR
SCHEMBL2284127 0.71 AHR (1.00) AHR
SCHEMBL6468968 0.70 AHR (0.60) AHR
SCHEMBL29353316 0.68 AHR (1.00) AHR
SCHEMBL2281954 0.68 AHR (1.00) AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1608306-A2 ALKYL-SUBSTITUTED PCDF AS A TREATMENT FOR PROSTATE CANCER THE TEXAS A & M UNIVERSITY SYSTEM (US) 2005-12-28 EP claimed
US-20050143450-A1 Alkyl PCDF as a treatment for prostate cancer TEXAS A&M UNIVERSITY SYSTEM (US) 2005-06-30 US claimed
WO-2005032452-A2 ALKYL-SUBSTITUTED PCDF AS A TREATMENT FOR PROSTATE CANCER TEXAS A & M UNIVERSITY SYSTEM (US) 2005-04-14 WO claimed
EP-1140047-B1 ENDOCRINE THERAPY FOR BREAST CANCER: COMBINED TREATMENT WITH TAMOXIFEN PLUS ALKYL PCDFS TEXAS A & M UNIV SYS (US) 2003-10-29 EP claimed
US-6136845-A ANTITUMOR AGENTS; MIXTURE CONTAINING POLYCHLORINATED DIBENZOFURAN THE TEXAS A&M UNIVERSITY SYSTEM (US) 2000-10-24 US claimed
US-5516790-A Synthesis and application of alkyl-substituted dibenzofurans as antitumorigenic agents TEXAS A&M UNIVERSITY SYSTEM TECHNOLOGY LICENSING OFFICE (US) 1996-05-14 US claimed
EP-1608306-A2 ALKYL-SUBSTITUTED PCDF AS A TREATMENT FOR PROSTATE CANCER THE TEXAS A & M UNIVERSITY SYSTEM (US) 2005-12-28 EP disclosed
US-20050143450-A1 Alkyl PCDF as a treatment for prostate cancer TEXAS A&M UNIVERSITY SYSTEM (US) 2005-06-30 US disclosed
WO-2005032452-A2 ALKYL-SUBSTITUTED PCDF AS A TREATMENT FOR PROSTATE CANCER TEXAS A & M UNIVERSITY SYSTEM (US) 2005-04-14 WO disclosed
EP-1140047-B1 ENDOCRINE THERAPY FOR BREAST CANCER: COMBINED TREATMENT WITH TAMOXIFEN PLUS ALKYL PCDFS TEXAS A & M UNIV SYS (US) 2003-10-29 EP disclosed
EP-1140047-A2 ENDOCRINE THERAPY FOR BREAST CANCER: COMBINED TREATMENT WITH TAMOXIFEN PLUS ALKYL PCDFS THE TEXAS A&M UNIVERSITY SYSTEM (US) 2001-10-10 EP disclosed
US-6136845-A ANTITUMOR AGENTS; MIXTURE CONTAINING POLYCHLORINATED DIBENZOFURAN THE TEXAS A&M UNIVERSITY SYSTEM (US) 2000-10-24 US disclosed
WO-2000037065-A2 ENDOCRINE THERAPY FOR BREAST CANCER: COMBINED TREATMENT WITH TAMOXIFEN PLUS ALKYL PCDFS THE TEXAS A & M UNIVERSITY SYSTEM (US) 2000-06-29 WO disclosed
US-5516790-A Synthesis and application of alkyl-substituted dibenzofurans as antitumorigenic agents TEXAS A&M UNIVERSITY SYSTEM TECHNOLOGY LICENSING OFFICE (US) 1996-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050143450-A1 Alkyl PCDF as a treatment for prostate cancer KLK3, ACP3, AR AHR 379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.