Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4972789 | 0.84 | TRPV1 (0.81) | TRPV1 | |
| SCHEMBL27600421 | 0.83 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL6449846 | 0.78 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL4971955 | 0.77 | TRPV1 (0.78) | TRPV1 | |
| SCHEMBL6471306 | 0.76 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL4919140 | 0.74 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL14283441 | 0.74 | TRPV1 (0.79) | TRPV1 | |
| SCHEMBL4972387 | 0.74 | TRPV1 (0.83) | TRPV1 | |
| SCHEMBL14283302 | 0.74 | TRPV1 (0.84) | TRPV1 | |
| SCHEMBL4975222 | 0.74 | TRPV1 (0.84) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581225-A1 | COMBINATION THERAPY FOR THE TREATMENT OF PAIN | NEUROGEN CORPORATION (US) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004054582-A1 | COMBINATION THERAPY FOR THE TREATMENT OF PAIN | NEUROGEN CORPORATION (US) | 2004-07-01 | — | — | WO | disclosed |