SCHEMBL6465875

SCHEMBL6465875

CCCCNC(=O)c1ccccc1C[C@@H](O)C[C@@H](Cc1ccccc1)C(=O)N[C@H]1c2ccccc2C[C@H]1O

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
VIPR2 P41587 19/20 0.57
MMP1 P03956 1/20 0.48
MMP2 P08253 1/20 0.48
MMP9 P14780 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6465881 1.00 VIPR2 (0.57) VIPR2MMP1MMP2MMP9
SCHEMBL6469198 0.87 VIPR2 (0.55) VIPR2
SCHEMBL6469195 0.87 VIPR2 (0.55) VIPR2
SCHEMBL6469450 0.85 VIPR2 (0.54) VIPR2MMP1MMP2MMP9
SCHEMBL6469452 0.85 VIPR2 (0.54) VIPR2MMP1MMP2MMP9
SCHEMBL6468238 0.84 MMP1 (0.64) VIPR2MMP1MMP2MMP9
SCHEMBL6466122 0.82 VIPR2 (0.69) VIPR2MMP1MMP2MMP9
SCHEMBL6468083 0.82 VIPR2 (0.62) VIPR2MMP2MMP9
SCHEMBL6469322 0.82 VIPR2 (0.64) VIPR2MMP1MMP2MMP9
SCHEMBL7300250 0.81 VIPR2 (0.70) VIPR2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016094706-A1 CURABLE NANO-COMPOSITES FOR ADDITIVE MANUFACTURING OF LENSES SCHMUTZ IP, LLC (US) 2016-06-16 WO claimed
US-20050038019-A1 Hydroxy substituted amides for the treatment of alzheimer's disease PHARMACIA & UPJOHN 2005-02-17 US claimed
EP-1443923-A1 HYDROXY SUBSTITUTED AMIDES FOR THE TREATMENT OF ALZHEIMER'S DISEASE Elan Pharmaceuticals, Inc. (US) 2004-08-11 EP claimed
WO-2003037325-A1 HYDROXY SUBSTITUTED AMIDES FOR THE TREATMENT OF ALZHEIMER'S DISEASE ELAN PHARMACEUTICALS, INC. (US) 2003-05-08 WO claimed
EP-3615641-A1 LUBRICATING COMPOSITION Shell Internationale Research Maatschappij B.V. (NL) 2020-03-04 EP disclosed
WO-2018197312-A1 LUBRICATING COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2018-11-01 WO disclosed
EP-3227414-B1 USE FOR REDUCING LOW SPEED PRE-IGNITION SHELL INT RESEARCH (NL) 2018-09-12 EP disclosed
EP-3227414-A1 METHOD FOR REDUCING LOW SPEED PRE-IGNITION Shell Internationale Research Maatschappij B.V. (NL) 2017-10-11 EP disclosed
EP-3197986-A1 LUBRICATING COMPOSITION Shell Internationale Research Maatschappij B.V. (NL) 2017-08-02 EP disclosed
EP-3158034-A1 LUBRICATING COMPOSITION Shell Internationale Research Maatschappij B.V. (NL) 2017-04-26 EP disclosed
WO-2016184842-A1 LUBRICATING COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2016-11-24 WO disclosed
WO-2016156328-A1 USE OF A LUBRICATING COMPOSITION COMPRISING A HINDERED AMINE LIGHT STABILIZER FOR IMPROVED PISTON CLEANLINESS IN AN INTERNAL COMBUSTION ENGINE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2016-10-06 WO disclosed
CN-104099169-B A kind of composite calcium sulfonate grease lubricant and preparation method thereof 山东北方淄特特种油股份有限公司 2016-06-29 CN disclosed
WO-2016087379-A1 METHOD FOR REDUCING LOW SPEED PRE-IGNITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2016-06-09 WO disclosed
WO-2016046133-A1 LUBRICATING COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2016-03-31 WO disclosed
WO-2016032782-A1 METHODS FOR LUBRICATING A DIAMOND-LIKE CARBON COATED SURFACE, ASSOCIATED LUBRICATING OIL COMPOSITIONS AND ASSOCIATED SCREENING METHODS SHELL OIL COMPANY (US) 2016-03-03 WO disclosed
WO-2015193395-A1 LUBRICATING COMPOSITION SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2015-12-23 WO disclosed
US-20050038019-A1 Hydroxy substituted amides for the treatment of alzheimer's disease PHARMACIA & UPJOHN 2005-02-17 US disclosed
EP-1454316-A2 LUBRICANT FOR MAGNETIC RECORDING MEDIUM AND USE THEREOF Pennzoil-Quaker State Company (US) 2004-09-08 EP disclosed
WO-2003030151-A2 LUBRICANT FOR MAGNETIC RECORDING MEDIUM AND USE THEREOF PENNZOIL-QUAKER STATE COMPANY (US) 2003-04-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038019-A1 Hydroxy substituted amides for the treatment of alzheimer's disease BACE1, APP, BACE2 VIPR2 2131/4885MMP1 1095/4885MMP2 357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.