Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.35 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NAA50 | Q9GZZ1 | 2/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10290632 | 0.89 | TRPV1 (0.39) | POLBTRPV1BAZ2ATSHRKDM4E | |
| SCHEMBL2726629 | 0.89 | TRPV1 (0.39) | POLBTRPV1BAZ2ATSHRKDM4E | |
| SCHEMBL2725310 | 0.88 | TSHR (0.37) | POLBTRPV1BAZ2ATSHRKDM4E | |
| SCHEMBL2712515 | 0.88 | POLB (0.36) | POLBTRPV1BAZ2ATSHRKDM4E | |
| SCHEMBL10290106 | 0.88 | TSHR (0.37) | POLBTRPV1BAZ2ATSHRKDM4E | |
| SCHEMBL6468341 | 0.87 | TRPV1 (0.38) | POLBTRPV1BAZ2ATSHRKDM4E | |
| SCHEMBL2726312 | 0.86 | POLB (0.40) | POLBTRPV1BAZ2ATSHRGRM5 | |
| SCHEMBL2713512 | 0.86 | KDM4E (0.42) | POLBTRPV1BAZ2ATSHRKDM4E | |
| SCHEMBL2712501 | 0.85 | KDM4E (0.40) | POLBTRPV1BAZ2ATSHRKDM4E | |
| SCHEMBL6467555 | 0.85 | TRPV1 (0.41) | POLBTRPV1BAZ2ATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |