Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.76 |
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6455635 | 0.92 | F10 (0.68) | F10ARMAPTMEN1ALDH1A1 | |
| SCHEMBL4466805 | 0.87 | F10 (1.00) | F10AR | |
| SCHEMBL3426142 | 0.85 | F10 (0.84) | F10ARMAPTMEN1ALDH1A1 | |
| SCHEMBL6455260 | 0.84 | F10 (0.68) | F10ARMAPTMEN1ALDH1A1 | |
| SCHEMBL6455289 | 0.84 | F10 (0.67) | F10ARMAPTMEN1ALDH1A1 | |
| SCHEMBL6462937 | 0.83 | F10 (0.78) | F10ARMAPTMEN1ALDH1A1 | |
| SCHEMBL6457868 | 0.82 | F10 (0.68) | F10ARMEN1ALDH1A1KMT2A | |
| SCHEMBL6461804 | 0.81 | F10 (0.65) | F10ARMEN1ALDH1A1KMT2A | |
| SCHEMBL6454451 | 0.81 | F10 (0.66) | F10ARMEN1ALDH1A1KMT2A | |
| SCHEMBL4463259 | 0.80 | F10 (0.74) | F10ARKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050256107-A1 | New substituted thiophene carboxamides, process for their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256107-A1 | New substituted thiophene carboxamides, process for their preparation and their use as medicaments | OTC, TPMT, ABCG2 | F10 1901/4885AR 3491/4885MAPT 1066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.