Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.74 |
| ▸ | AR | P10275 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4473851 | 0.90 | F10 (0.61) | F10ARKMT2A | |
| SCHEMBL4004686 | 0.87 | F10 (0.57) | F10AR | |
| SCHEMBL5531632 | 0.86 | F10 (0.56) | F10AR | |
| SCHEMBL4466805 | 0.85 | F10 (1.00) | F10AR | |
| SCHEMBL4472368 | 0.84 | F10 (0.59) | F10ARKMT2A | |
| SCHEMBL4477814 | 0.83 | F10 (0.75) | F10ARMAPK1KMT2A | |
| SCHEMBL4459710 | 0.82 | F10 (0.60) | F10ARKMT2A | |
| SCHEMBL4473493 | 0.81 | F10 (0.62) | F10ARMAPK1KMT2A | |
| SCHEMBL6457868 | 0.81 | F10 (0.68) | F10ARLMNAMAPK1KMT2A | |
| SCHEMBL6466092 | 0.80 | F10 (0.76) | F10ARMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7476663-B2 | Substituted thiophene carboxamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-01-13 | — | — | US | disclosed |
| US-20050277628-A1 | Substituted thiophene carboxamides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050277628-A1 | Substituted thiophene carboxamides | OTC, SLC22A8, DDC | F10 2132/4885AR 2088/4885LMNA 4288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.