Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1182292 | 0.89 | LDHA (0.52) | HPGDSKDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL40547 | 0.87 | KDM4E (0.61) | CYP2A6HPGDSKDM4ELMNACYP1A2 | |
| SCHEMBL29419035 | 0.87 | KDM4E (0.61) | CYP2A6HPGDSKDM4ELMNACYP1A2 | |
| SCHEMBL12523554 | 0.85 | MAPK1 (0.56) | HPGDSRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL15747736 | 0.83 | NPC1 (0.53) | HPGDSKDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3341229 | 0.83 | KDM4E (0.54) | CYP2A6KDM4ELMNACYP1A2POLB | |
| SCHEMBL301762 | 0.82 | KDM4E (0.65) | CYP2A6KDM4ELMNACYP1A2POLB | |
| SCHEMBL3985205 | 0.82 | KDM4E (0.65) | CYP2A6KDM4ELMNACYP1A2POLB | |
| SCHEMBL29461566 | 0.82 | KDM4E (0.65) | CYP2A6KDM4ELMNACYP1A2POLB | |
| SCHEMBL51343 | 0.82 | KDM4E (0.65) | CYP2A6KDM4ELMNACYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9065062-B2 | Cross-linkable iridium complexes and organic light-emitting devices using the same | UNIVERSAL DISPLAY CORPORATION (US) | 2015-06-23 | — | — | US | disclosed |
| US-20120107989-A1 | CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME | UNIVERSAL DISPLAY CORPORATION | 2012-05-03 | — | — | US | disclosed |
| US-8119255-B2 | First and second electrode; a first organic layer between the electrodes; the first organic layer is a non-electroluminescent, cross-linked metal complex; and a second organic layer is an emissive electroluminescent organic material | UNIVERSAL DISPLAY CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| US-20080220265-A1 | Cross-linkable Iridium Complexes and Organic Light-Emitting Devices Using the Same | UNIVERSAL DISPLAY CORPORATION (US) | 2008-09-11 | — | — | US | disclosed |
| WO-2008073440-A2 | CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME | UNIVERSAL DISPLAY CORPORATION (US) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080220265-A1 | Cross-linkable Iridium Complexes and Organic Light-Emitting Devices Using the Same | MTCL3, LIG4, L1CAM | CYP2A6 2031/4885HPGDS 4117/4885KDM4E 2803/4885 |
| US-20120107989-A1 | CROSS-LINKABLE IRIDIUM COMPLEXES AND ORGANIC LIGHT-EMITTING DEVICES USING THE SAME | MTCL3, LIG4, L1CAM | CYP2A6 2031/4885HPGDS 4117/4885KDM4E 2803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.