SCHEMBL6466458

SCHEMBL6466458

Cc1ccc(S(=O)(=O)N(C(N)=O)c2ccc(C)c(N(C(N)=O)S(=O)(=O)c3ccc(C)cc3)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.48
KDM4E B2RXH2 1/20 0.48
TP53 P04637 7/20 0.46
MAPT P10636 3/20 0.46
CYP2C9 P11712 1/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MCOLN3 Q8TDD5 1/20 0.44
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
THRB P10828 1/20 0.42
HPGD P15428 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6243993 0.85 LMNA (0.62) LMNAKDM4ETP53MAPTCYP2C9
SCHEMBL27991408 0.85 LMNA (0.62) LMNAKDM4ETP53MAPTCYP2C9
SCHEMBL6241748 0.82 LMNA (0.55) LMNAKDM4ETP53MAPTCYP2C9
SCHEMBL6326490 0.81 C5AR1 (0.53) LMNAKDM4ETP53MAPTCYP2C9
SCHEMBL6244985 0.81 LMNA (0.57) LMNAKDM4ETP53MAPTCYP2C9
SCHEMBL6324948 0.80 LMNA (0.63) LMNAKDM4ETP53MAPTMEN1
SCHEMBL6322946 0.78 TP53 (0.59) LMNAKDM4ETP53MAPTCYP2C9
SCHEMBL7999295 0.78 LMNA (0.76) LMNAKDM4ETP53MAPTMEN1
SCHEMBL1878018 0.78 CA12 (0.58) LMNAKDM4ETP53MAPTCYP2C9
SCHEMBL28244533 0.78 KMT2A (0.63) LMNAKDM4ETP53MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
US-5851951-A Heat sensitive recording material OJI PAPER CO., LTD. (JP) 1998-12-22 US disclosed
EP-0792754-A2 Heat sensitive recording material Oji Paper Co., Ltd. (JP) 1997-09-03 EP disclosed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US disclosed