SCHEMBL6466516

SCHEMBL6466516

CC1(O)C(O)C(CO)OC1n1cc(C#N)c2c(=O)[nH]cnc21

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 7/20 0.45
ADA P00813 1/20 0.38
HIF1A Q16665 1/20 0.38
PAX8 Q06710 1/20 0.38
ADORA3 P0DMS8 8/20 0.38
ADORA1 P30542 5/20 0.38
ADORA2B P29275 4/20 0.38
ALOX15 P16050 1/20 0.36
ADK P55263 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6838191 0.85 ADORA2A (0.47) ADORA2AADAADORA3ADORA1ADORA2B
SCHEMBL1738696 0.82 ADORA2A (0.61) ADORA2AADAHIF1APAX8ADORA3
SCHEMBL2786188 0.82 ADORA2A (0.61) ADORA2AADAHIF1APAX8ADORA3
SCHEMBL2786193 0.82 ADORA2A (0.61) ADORA2AADAHIF1APAX8ADORA3
SCHEMBL2786772 0.82 ADORA2A (0.61) ADORA2AADAHIF1APAX8ADORA3
SCHEMBL12447395 0.82 ADORA2A (0.61) ADORA2AADAHIF1APAX8ADORA3
SCHEMBL6833725 0.82 ADORA2A (0.46) ADORA2AADAPAX8ADORA3ADORA1
SCHEMBL6833685 0.81 ADORA2A (0.46) ADORA2AADAPAX8ADORA3ADORA1
SCHEMBL13604051 0.80 ADORA2A (0.51) ADORA2AHIF1APAX8ADORA3ADORA1
SCHEMBL31093987 0.80 PAX8 (0.55) HIF1APAX8ADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1501850-A2 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION GENELABS TECHNOLOGIES, INC. (US) 2005-02-02 EP disclosed
US-20040063658-A1 Nucleoside derivatives for treating hepatitis C virus infection GENELABS TECHNOLOGIES, INC. 2004-04-01 US disclosed
WO-2003093290-A2 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION GENELABS TECHNOLOGIES, INC. (US) 2003-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063658-A1 Nucleoside derivatives for treating hepatitis C virus infection HAVCR2, PNP, NTPCR ADORA2A 174/4885ADA 13/4885HIF1A 3299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.