Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 5/20 | 0.39 |
| ▸ | SCD | O00767 | 4/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2725873 | 1.00 | SCD5 (0.39) | SCD5SCDBACE1HCRTR1HCRTR2 | |
| SCHEMBL2725874 | 1.00 | SCD5 (0.39) | SCD5SCDBACE1HCRTR1HCRTR2 | |
| SCHEMBL10290176 | 1.00 | SCD5 (0.39) | SCD5SCDBACE1HCRTR1HCRTR2 | |
| SCHEMBL2726988 | 0.91 | SMN1; SMN2 (0.38) | SCD5SCDHCRTR1HCRTR2TRPV1 | |
| SCHEMBL6468066 | 0.91 | BACE1 (0.37) | SCD5SCDBACE1HCRTR1HCRTR2 | |
| SCHEMBL2726485 | 0.89 | BACE1 (0.39) | SCD5SCDBACE1HCRTR1HCRTR2 | |
| SCHEMBL2726490 | 0.89 | BACE1 (0.39) | SCD5SCDBACE1HCRTR1HCRTR2 | |
| SCHEMBL2726488 | 0.89 | BACE1 (0.39) | SCD5SCDBACE1HCRTR1HCRTR2 | |
| SCHEMBL10290013 | 0.89 | SCD5 (0.39) | SCD5SCDBACE1HCRTR1HCRTR2 | |
| SCHEMBL2725377 | 0.89 | SCD5 (0.39) | SCD5SCDBACE1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |