Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 7/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928677 | 0.86 | CNR2 (0.46) | MDM2TP53GRIN1GRIN2BADORA1 | |
| SCHEMBL3920234 | 0.82 | CNR1 (0.55) | MDM2CNR2CNR1 | |
| SCHEMBL28758204 | 0.79 | CNR1 (0.45) | MDM2CHRM4CNR2ALDH1A1POLB | |
| SCHEMBL1719194 | 0.77 | GRIN1 (0.46) | PIN1MDM2GRIN1GRIN2BADORA1 | |
| SCHEMBL3919634 | 0.75 | CNR1 (0.47) | CHRM4CNR2TRPV4CNR1 | |
| SCHEMBL3919284 | 0.74 | CNR1 (0.51) | MDM2CNR2CNR1 | |
| SCHEMBL3921306 | 0.74 | ABL1 (0.40) | MDM2TP53OPRM1OPRK1 | |
| SCHEMBL3923357 | 0.72 | CNR1 (0.44) | CHRM4CNR2TRPV4CNR1 | |
| SCHEMBL1719589 | 0.72 | GRIN1 (0.49) | GRIN1GRIN2BADORA1CNR2POLB | |
| SCHEMBL3922942 | 0.72 | ALOX5 (0.44) | MDM2CNR2CNR1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603929-A1 | SOLUBLE GROUP-10 ALPHA-DIIMINE CATALYST PRECURSORS | ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1583742-A1 | NOVEL CB 1 RECEPTOUR INVERSE AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004083224-A1 | SOLUBLE GROUP-10 α-DIIMINE CATALYST PRECURSORS, | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-09-30 | — | — | WO | disclosed |
| WO-2004060870-A1 | NOVEL CB 1 RECEPTOUR INVERSE AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-07-22 | — | — | WO | disclosed |