SCHEMBL6467445

SCHEMBL6467445

CC(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1ccc2c3ccc(-n4c5ccc(C(C)(C)C)cc5c5cc(C(C)(C)C)ccc54)cc3n(-c3ccc4ccccc4c3)c2c1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.39
RORA P35398 2/20 0.33
RORC P51449 2/20 0.33
RORB Q92753 2/20 0.33
UGT2B7 P16662 1/20 0.33
KCNH2 Q12809 1/20 0.32
DNMT1 P26358 3/20 0.32
PGR P06401 1/20 0.32
BCL2 P10415 1/20 0.31
MCL1 Q07820 1/20 0.31
PTGES2 Q9H7Z7 1/20 0.31
MAPK9 P45984 1/20 0.31
MAPK10 P53779 1/20 0.31
KDM1A O60341 1/20 0.31
PTGES O14684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2604398 0.91 KCNH2 (0.37) PPARGRORARORCRORBKCNH2
SCHEMBL15788346 0.89 PPARG (0.38) PPARGRORARORCRORBKCNH2
SCHEMBL2604405 0.87 KCNH2 (0.36) PPARGRORARORCRORBKCNH2
SCHEMBL17774073 0.86 KCNH2 (0.40) PPARGRORARORCRORBKCNH2
SCHEMBL20961290 0.85 RORA (0.41) PPARGRORARORCRORBUGT2B7
SCHEMBL19735303 0.85 KDM4E (0.41) PPARGRORARORCRORBKCNH2
SCHEMBL2604407 0.85 KCNH2 (0.39) PPARGRORARORCRORBKCNH2
SCHEMBL9886208 0.84 PPARG (0.39) PPARGRORARORCRORBDNMT1
SCHEMBL25833416 0.84 PPARG (0.41) PPARGRORARORCRORBDNMT1
SCHEMBL17774018 0.82 NPY5R (0.34) PPARGRORARORCRORB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2448031-A2 Photoelectric conversion device and solid-state imaging device Fujifilm Corporation (JP) 2012-05-02 EP disclosed