Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | KDM5C | P41229 | 3/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.49 |
| ▸ | KDM6B | O15054 | 2/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.49 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.49 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.46 |
| ▸ | GLRB | P48167 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2727658 | 0.93 | CFTR (0.43) | KDM4EKDM5CKDM4CKDM6BKDM2A | |
| SCHEMBL2727496 | 0.85 | GLRA3 (0.46) | KDM4EKDM5CKDM4CKDM6BKDM2A | |
| SCHEMBL2727661 | 0.82 | GLRA3 (0.43) | KDM4EKDM5CKDM4CKDM6BKDM2A | |
| SCHEMBL475508 | 0.77 | GLRA3 (0.70) | KDM4EKDM5CKDM4CKDM6BKDM2A | |
| SCHEMBL30163064 | 0.76 | KDM4E (0.63) | KDM4EKDM5CKDM4CKDM6BKDM2A | |
| SCHEMBL29218201 | 0.76 | KDM4E (0.63) | KDM4EKDM5CKDM4CKDM6BKDM2A | |
| SCHEMBL21144538 | 0.76 | TSHR (0.61) | KDM4EKDM5CKDM4CKDM6BKDM2A | |
| SCHEMBL29907727 | 0.73 | GLRA3 (0.45) | KDM4EKDM5CKDM4CKDM6BKDM2A | |
| SCHEMBL12248226 | 0.73 | GLRA3 (0.45) | KDM4EKDM5CKDM4CKDM6BKDM2A | |
| SCHEMBL11956572 | 0.73 | TSHR (0.69) | KDM4EKDM5CKDM4CKDM6BKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |