Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 6/20 | 0.39 |
| ▸ | STS | P08842 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468734 | 0.85 | LMNA (0.58) | LMNAHSD17B10ESR1MAPTUSP2 | |
| SCHEMBL6462626 | 0.82 | STS (0.42) | LMNAHSD17B10HRH3ESR1STS | |
| SCHEMBL6464758 | 0.80 | HRH3 (0.39) | LMNAHSD17B10HRH3ESR1STS | |
| SCHEMBL7704384 | 0.80 | HRH3 (0.39) | LMNAHSD17B10HRH3ESR1STS | |
| SCHEMBL6527877 | 0.79 | LMNA (0.41) | LMNAHSD17B10HRH3ESR1STS | |
| SCHEMBL7702820 | 0.79 | LMNA (0.41) | LMNAHSD17B10HRH3ESR1STS | |
| SCHEMBL6467659 | 0.79 | LMNA (0.41) | LMNAHSD17B10HRH3ESR1STS | |
| SCHEMBL6463763 | 0.79 | HRH3 (0.47) | LMNAHSD17B10HRH3ESR1STS | |
| SCHEMBL6468338 | 0.79 | HRH3 (0.47) | LMNAHSD17B10HRH3ESR1STS | |
| SCHEMBL6468651 | 0.79 | HRH3 (0.47) | LMNAHSD17B10HRH3ESR1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881728-B1 | 14-β, 17-α-hydroxymethylandrostane derivatives as androgens | AKZO NOBEL N.V. (NL) | 2005-04-19 | — | — | US | disclosed |
| EP-1163259-B1 | 14.BETA.,17-ALPHA-HYDROXYMETHYLANDROSTANE DERIVATIVES AS ANDROGENS | AKZO NOBEL NV (NL) | 2002-11-20 | — | — | EP | disclosed |