Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3556404 | 0.80 | MAPT (0.38) | MAPTHTR2BALDH1A1 | |
| SCHEMBL1051061 | 0.73 | MAPT (0.40) | MAPTHTR2BALDH1A1 | |
| SCHEMBL2438716 | 0.73 | MAPT (0.41) | MAPTHTR2BALDH1A1 | |
| SCHEMBL9381730 | 0.72 | MAPT (0.36) | MAPTHTR2BALDH1A1 | |
| SCHEMBL9568876 | 0.70 | HTR2B (0.40) | MAPTHTR2BALDH1A1 | |
| SCHEMBL16742562 | 0.69 | MAPT (0.45) | MAPTHTR2BALDH1A1 | |
| SCHEMBL10771875 | 0.66 | — | — | |
| SCHEMBL10465533 | 0.66 | MAPT (0.45) | MAPTHTR2BALDH1A1 | |
| SCHEMBL13999711 | 0.66 | MAPT (0.39) | MAPTHTR2BALDH1A1 | |
| SCHEMBL20130304 | 0.66 | HTR2B (0.35) | MAPTHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |