Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13380097 | 0.84 | MME (0.53) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL7327700 | 0.84 | MME (0.53) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL8475947 | 0.81 | MME (0.50) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL31307586 | 0.81 | MME (0.50) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL371120 | 0.81 | MME (0.50) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL16011617 | 0.81 | MME (0.50) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL18620679 | 0.78 | MME (0.47) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL22209522 | 0.78 | MME (0.47) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL15223598 | 0.78 | MME (0.59) | MMECYP2C9ALDH1A1THRBCYP2C19 | |
| SCHEMBL6467692 | 0.78 | CA14 (0.43) | ALDH1A1BIRC2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012058269-A2 | METHODS OF TREATING CANCER AND OTHER DISEASES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2012-05-03 | — | — | WO | disclosed |