Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860088 | 0.83 | EPHX1 (0.43) | EPHX1GAAKDM4EL3MBTL1BCHE | |
| SCHEMBL8371398 | 0.77 | EPHX1 (0.68) | EPHX1GAAHTTBCHEKAT2B | |
| SCHEMBL1023586 | 0.71 | KAT2B (0.43) | EPHX1L3MBTL1KAT2BBAZ2BACACB | |
| Hydrochloric Acid SCHEMBL4446983 | 0.71 | EPHX1 (0.54) | EPHX1GAAEPHX2 | |
| SCHEMBL25283458 | 0.71 | EPHX1 (0.38) | EPHX1L3MBTL1KAT2BBAZ2BSMN1; SMN2 | |
| SCHEMBL15233241 | 0.71 | KAT2B (0.49) | EPHX1BCHEKAT2BBAZ2BKCNA3 | |
| SCHEMBL13748646 | 0.70 | EPHX1 (0.41) | EPHX1GAAKAT2BBAZ2BEPHX2 | |
| Hydrochloric Acid SCHEMBL3966985 | 0.69 | KAT2B (0.42) | EPHX1L3MBTL1KAT2BBAZ2BACACB | |
| SCHEMBL1023585 | 0.69 | KAT2B (0.39) | EPHX1L3MBTL1KAT2BBAZ2B | |
| SCHEMBL12850048 | 0.69 | EPHX2 (0.43) | EPHX1GAAHTTBCHEKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |