SCHEMBL6468405

SCHEMBL6468405

CCCc1nc(COOCC)c(COOCC)[nH]1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.32
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9613567 0.76
SCHEMBL3701880 0.71 GLA (0.39) GLAKDM4EPOLB
SCHEMBL28286871 0.70 GLA (0.38) GLAKDM4EPOLB
SCHEMBL3693696 0.70 GLA (0.38) GLAKDM4EPOLB
SCHEMBL3697669 0.70 GLA (0.38) GLAKDM4EPOLB
SCHEMBL28291675 0.69 GLA (0.33) GLAPOLB
SCHEMBL4356818 0.67 GLA (0.35) GLAKDM4EPOLB
SCHEMBL3701645 0.63 GLA (0.39) GLAKDM4EPOLB
SCHEMBL3698722 0.62 ADORA1 (0.39) GLA
SCHEMBL28285520 0.62 ADORA1 (0.39) GLAKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012069025-A1 (5-METHYL-2-OXO-1,3-DIOXOL-4-YLMETHYL)-4-(1-HYDROXY-1-METHYL-PROPYL)-2-PROPYL-1-[2'- (1H-TETRAZOL-5-YL)BIPHENYL-4-YL-METHYL]IMIDAZOLE-5-CARBOXYLATE AS AN IMPURITY OF OLMESARTAN MEDOXOMIL AND A METHOD OF ITS PREPARATION ZENTIVA, K.S. (CZ) 2012-05-31 WO disclosed
WO-2012055380-A1 A METHOD OF OBTAINING OLMESARTAN MEDOXOMIL ZENTIVA, K. S. (CZ) 2012-05-03 WO disclosed