SCHEMBL4356818

SCHEMBL4356818

CCCc1nc(CO)c(CO)[nH]1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.35
ADORA3 P0DMS8 2/20 0.33
ADORA2A P29274 2/20 0.33
ADORA1 P30542 2/20 0.33
POLB P06746 1/20 0.33
KDM4C Q9H3R0 1/20 0.32
GPR84 Q9NQS5 5/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
KMT2A Q03164 1/20 0.30
MAPK1 P28482 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4356446 0.89 ALDH1A1 (0.42) GPR84ALDH1A1MAPK1
SCHEMBL9081675 0.87 GPR84 (0.45) GPR84ALDH1A1MAPK1
SCHEMBL4356039 0.85 GPR84 (0.46) GPR84ALDH1A1MAPK1
SCHEMBL9081811 0.85 GPR84 (0.46) GPR84ALDH1A1MAPK1
SCHEMBL9081998 0.85 GPR84 (0.46) GPR84ALDH1A1MAPK1
SCHEMBL9082364 0.85 GPR84 (0.46) GPR84ALDH1A1MAPK1
SCHEMBL9082927 0.85 GPR84 (0.46) GPR84ALDH1A1MAPK1
SCHEMBL9082048 0.85 GPR84 (0.46) GPR84ALDH1A1MAPK1
SCHEMBL4353447 0.83 ADORA1 (0.39) ADORA3ADORA2AADORA1KDM4EALDH1A1
SCHEMBL7558596 0.81 KDM4E (0.38) KDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111471016-B Synthesis method of 2-propylimidazole-4, 5-dicarboxylic acid 湖南华腾医药有限公司 2023-08-15 CN disclosed
US-7614145-B2 Method for manufacturing multilayer circuit board and resin base material ZEON CORPORATION (JP) 2009-11-10 US disclosed
US-20080217617-A1 Thin Film Transistor, Wiring Board and Methods of Manufacturing the Same ZEON CORPORATION (JP) 2008-09-11 US disclosed
US-20050153059-A1 Partial plating method, partially-plated resin base, method for manufacturing multilayered circuit board ZEON CORPORATION (JP) 2005-07-14 US disclosed
US-20040237295-A1 Multilayer circuit board and resin base material, and its production method ZEON CORPORATION (JP) 2004-12-02 US disclosed
EP-0611758-B1 Process for synthesizing 4-halo-5(hydroxymethyl) imidazole compounds and certain novel 4-halo-5(hydroxymethyl) imidazole compounds SHIKOKU CHEM (JP) 1996-10-16 EP disclosed
US-5514811-A Process for synthesizing 4-halo-5-(hydroxymethyl) imidazole compounds SHIKOKU CHEMICALS CORPORATION (JP) 1996-05-07 US disclosed
EP-0611758-A1 Process for synthesizing 4-halo-5(hydroxymethyl) imidazole compounds and certain novel 4-halo-5(hydroxymethyl) imidazole compounds SHIKOKU CHEMICALS CORPORATION (JP) 1994-08-24 EP disclosed