Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 8/20 | 0.33 |
| ▸ | CPT2 | P23786 | 7/20 | 0.33 |
| ▸ | CPT1B | Q92523 | 4/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468357 | 0.89 | CPT1A (0.35) | CPT1ACPT2CPT1BTRPV1HCRTR1 | |
| SCHEMBL6466357 | 0.88 | TRPV1 (0.38) | CPT1ACPT2CPT1BTRPV1HCRTR1 | |
| SCHEMBL2725976 | 0.86 | TRPV1 (0.36) | CPT1ACPT2CPT1BTRPV1HCRTR1 | |
| SCHEMBL6465338 | 0.86 | TRPV1 (0.36) | XIAPBIRC2CPT1ACPT2CPT1B | |
| SCHEMBL2727050 | 0.86 | TRPV1 (0.36) | XIAPBIRC2CPT1ACPT2CPT1B | |
| SCHEMBL6466450 | 0.85 | TRPV1 (0.36) | CPT1ACPT2CPT1BTRPV1AADAT | |
| SCHEMBL6466217 | 0.85 | BACE1 (0.36) | CPT1ACPT2CPT1BTRPV1AADAT | |
| SCHEMBL2728770 | 0.85 | BACE1 (0.36) | CPT1ACPT2CPT1BTRPV1AADAT | |
| SCHEMBL10290648 | 0.84 | HCRTR1 (0.39) | TRPV1HCRTR1HCRTR2 | |
| SCHEMBL6466854 | 0.84 | KCNK3 (0.37) | CPT1ACPT2CPT1BTRPV1AADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |