Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 17/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 17/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466450 | 0.92 | TRPV1 (0.36) | TRPV1PKM | |
| SCHEMBL6466357 | 0.92 | TRPV1 (0.38) | HCRTR1HCRTR2TRPV1PKM | |
| SCHEMBL6466456 | 0.91 | ADAM17 (0.36) | HCRTR1HCRTR2TRPV1PKM | |
| SCHEMBL6465338 | 0.90 | TRPV1 (0.36) | HCRTR1HCRTR2TRPV1PKM | |
| SCHEMBL2727050 | 0.90 | TRPV1 (0.36) | HCRTR1HCRTR2TRPV1PKM | |
| SCHEMBL2725976 | 0.90 | TRPV1 (0.36) | HCRTR1HCRTR2TRPV1PKM | |
| SCHEMBL6467817 | 0.89 | TRPV1 (0.35) | HCRTR1HCRTR2TRPV1PKM | |
| SCHEMBL6467766 | 0.89 | SCD5 (0.35) | HCRTR1HCRTR2TRPV1PKM | |
| SCHEMBL6466608 | 0.88 | TRPV1 (0.36) | HCRTR1HCRTR2TRPV1 | |
| SCHEMBL6466854 | 0.88 | KCNK3 (0.37) | TRPV1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |