Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.57 |
| ▸ | PREP | P48147 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CPT1A | P50416 | 2/20 | 0.48 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20705254 | 0.87 | AADAT (0.54) | AADATPREPCTRB1TMEM97SIGMAR1 | |
| SCHEMBL13209676 | 0.87 | AADAT (0.53) | AADATPREPSMN1; SMN2CTRB1TMEM97 | |
| SCHEMBL13576750 | 0.87 | AADAT (0.53) | AADATPREPSMN1; SMN2CTRB1TMEM97 | |
| SCHEMBL29394187 | 0.87 | AADAT (0.53) | AADATPREPSMN1; SMN2CTRB1TMEM97 | |
| SCHEMBL13209886 | 0.84 | AADAT (0.56) | AADATPREPCTRB1TMEM97SIGMAR1 | |
| SCHEMBL13209678 | 0.84 | AADAT (0.51) | AADATPREPCTRB1TMEM97SIGMAR1 | |
| SCHEMBL15453437 | 0.83 | CPT1A (0.57) | AADATCPT1ACPT1BTRPV1 | |
| SCHEMBL15453706 | 0.80 | CPT1A (0.54) | AADATCPT1ACPT1BTRPV1 | |
| SCHEMBL3556069 | 0.79 | AADAT (0.51) | AADATPREPCTRB1TMEM97SIGMAR1 | |
| SCHEMBL475512 | 0.79 | TRPV1 (0.46) | SMN1; SMN2CPT1ACPT1BTRPV1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |