SCHEMBL6468660

SCHEMBL6468660

Cc1cccc(C)c1C(=O)C(P=O)C(=O)c1c(C)cccc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ALDH1A1 P00352 4/20 0.36
HPGD P15428 3/20 0.35
KDM4E B2RXH2 3/20 0.35
HSD17B10 Q99714 2/20 0.35
GAA P10253 1/20 0.34
ALOX12 P18054 1/20 0.34
DDX3X O00571 1/20 0.33
GPR52 Q9Y2T5 1/20 0.33
FABP3 P05413 1/20 0.33
FABP4 P15090 1/20 0.33
HSP90AA1 P07900 1/20 0.33
ATM Q13315 1/20 0.33
HTT P42858 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
MAPT P10636 1/20 0.33
TYK2 P29597 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28114832 0.82 TYK2 (0.38) L3MBTL1TDP1NPC1RAB9AALDH1A1
SCHEMBL7175012 0.76 L3MBTL1 (0.46) L3MBTL1TDP1GPR52FABP3FABP4
SCHEMBL10137794 0.76 FFAR1 (0.45) L3MBTL1TDP1ALDH1A1HPGDKDM4E
SCHEMBL152304 0.75 L3MBTL1 (0.36) L3MBTL1TDP1NPC1RAB9AALDH1A1
SCHEMBL3397248 0.74 L3MBTL1 (0.40) L3MBTL1TDP1NPC1RAB9AALDH1A1
SCHEMBL6470319 0.73 L3MBTL1 (0.37) L3MBTL1TDP1NPC1RAB9AALDH1A1
SCHEMBL5994217 0.72 L3MBTL1 (0.39) L3MBTL1TDP1NPC1RAB9AALDH1A1
SCHEMBL27573925 0.72 L3MBTL1 (0.39) L3MBTL1TDP1NPC1RAB9AALDH1A1
SCHEMBL27521213 0.71 TDP1 (0.41) L3MBTL1TDP1NPC1RAB9AALDH1A1
SCHEMBL9356340 0.71 L3MBTL1 (0.42) L3MBTL1TDP1ALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050096406-A1 Reactive diluents and alkyd resin coating compositions PRETOT ROGER (CH) 2005-05-05 US disclosed
US-5534559-A UNSATURATED POLYESTERS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed