SCHEMBL6468779

SCHEMBL6468779

C=C(C)C(=O)OC=C(O)COCC(O)=COC(=O)C(=C)C

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
THRB P10828 1/20 0.37
TSHR P16473 3/20 0.36
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5981417 0.82 ALDH1A1 (0.39) ALDH1A1THRBTSHRTDP1
SCHEMBL16661384 0.82 ALDH1A1 (0.39) ALDH1A1THRBTSHRTDP1
SCHEMBL17853900 0.77 TSHR (0.37) ALDH1A1THRBTSHRAPEX1
SCHEMBL11600731 0.77 TSHR (0.50) ALDH1A1TSHRPOLBAPEX1TDP1
SCHEMBL11600727 0.77 TSHR (0.50) ALDH1A1TSHRPOLBAPEX1TDP1
SCHEMBL3516867 0.73 ALDH1A1 (0.48) ALDH1A1THRBTSHRTDP1
SCHEMBL5591839 0.72 ALDH1A1 (0.42) ALDH1A1THRBTSHRTDP1
SCHEMBL28054180 0.71 ALDH1A1 (0.41) ALDH1A1THRBTSHRTDP1
SCHEMBL36564 0.70
SCHEMBL28395506 0.70 ALDH1A1 (0.44) ALDH1A1THRBTSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0858392-B2 PROCESSES FOR PREPARING AND USING MOULDS HUNTSMAN ADVANCED MATERIALS UK (GB) 2005-10-12 EP disclosed
EP-0854783-B1 PROCESS FOR PRODUCING POLYMERIC LAYERS HAVING SELECTIVELY COLOURED REGIONS VANTICO LTD (GB) 2002-10-23 EP disclosed
EP-0593806-B1 Method for the preparation of a screen mesh for screen printing SCHABLONENTECHNIK KUFSTEIN AG (AT) 2002-04-17 EP disclosed
EP-0858392-B1 PROCESSES FOR PREPARING AND USING MOULDS AVECIA LTD (GB) 2000-12-20 EP disclosed
US-6133336-A FORMING A SELECTIVELY COLORED POLYMERIC LAYER, OR A THREE-DIMENSIONAL ARTICLE MADE OF POLYMERIC LAYERS, WHEREIN A PHOTOCURABLE PHOTOCOLORABLE COMPOSITION IS IRRADIATED WITH A LOW DOSE OF LIGHT TO CURE AND A HIGHER DOSE OF LIGHT TO COLOR ZENECA LIMITED (GB) 2000-10-17 US disclosed
US-6001298-A Method for making a mould ZENECA LIMITED (GB) 1999-12-14 US disclosed
EP-0858392-A2 PROCESSES FOR PREPARING AND USING MOULDS ZENECA LIMITED (GB) 1998-08-19 EP disclosed
EP-0854783-A1 PROCESS FOR PRODUCING POLYMERIC LAYERS HAVING SELECTIVELY COLOURED REGIONS ZENECA LIMITED (GB) 1998-07-29 EP disclosed
WO-1997017190-A2 PROCESSES FOR PREPARING AND USING MOULDS ZENECA LIMITED (GB) 1997-05-15 WO disclosed
WO-1997009168-A1 PROCESS FOR PRODUCING POLYMERIC LAYERS HAVING SELECTIVELY COLOURED REGIONS ZENECA LIMITED (GB) 1997-03-13 WO disclosed
EP-0403758-B1 Solid imaging method using compositions containing core-shell polymers DU PONT (US) 1995-07-05 EP disclosed
EP-0658812-A1 Process for the preparation of a printing screen Schablonentechnik Kufstein Aktiengesellschaft (AT) 1995-06-21 EP disclosed
US-5384007-A Process for manufacturing a screen printing stencil SCHABLONENTECHNIK KUESTEIN GES. M.B.H. (AT) 1995-01-24 US disclosed
EP-0593806-A1 Method for the preparation of a screen mesh for screen printing Schablonentechnik Kufstein Aktiengesellschaft (AT) 1994-04-27 EP disclosed
US-5002854-A Radiation Deflection E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-26 US disclosed
CN-1048934-A Utilize the solid imaging method of the photohardenable materials of self limiting thickness DU PONT (US) 1991-01-30 CN disclosed
CN-1048932-A Carry out the method for solid state image with heterogeneous photohardenable compositions DU PONT (US) 1991-01-30 CN disclosed
US-4987044-A Method and apparatus for maintaining desired exposure levels E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-22 US disclosed
CN-1046614-A The adjuvant that the photohardenable compositions shrinkage factor is reduced DU PONT (US) 1990-10-31 CN disclosed
CN-1046613-A Utilization realizes the method for solid state image by the photohardenable compositions of the self limiting thickness that is separated DU PONT (US) 1990-10-31 CN disclosed