Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6467307 | 0.99 | POLB (0.52) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL12567531 | 0.95 | POLB (0.49) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL14204968 | 0.92 | POLB (0.45) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL6727442 | 0.92 | POLB (0.52) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL14075891 | 0.91 | POLB (0.44) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL3792053 | 0.89 | POLB (0.56) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL6468969 | 0.89 | POLB (0.56) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL26418655 | 0.89 | POLB (0.56) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL3714963 | 0.89 | POLB (0.55) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL816232 | 0.88 | POLB (0.64) | POLBAPEX1HTTTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050040364-A1 | Liquid crystalline laterally polymerizable compounds | ROLIC AG (CH) | 2005-02-24 | — | — | US | disclosed |
| EP-1432673-A1 | LIQUID CRYSTALLINE \"LATERALLY POLYMERIZABLE\" COMPOUNDS | Rolic AG (CH) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003027056-A1 | LIQUID CRYSTALLINE 'LATERALLY POLYMERIZABLE' COMPOUNDS | ROLIC AG (CH) | 2003-04-03 | — | — | WO | disclosed |
| EP-1295863-A1 | Liquid crystalline \"laterally polymerizable\" compounds | Rolic AG (CH) | 2003-03-26 | — | — | EP | disclosed |