Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468969 | 0.92 | POLB (0.56) | POLBHTTAPEX1TDP1MAPT | |
| SCHEMBL3792053 | 0.92 | POLB (0.56) | POLBHTTAPEX1TDP1MAPT | |
| SCHEMBL3714963 | 0.92 | POLB (0.55) | POLBHTTAPEX1TDP1MAPT | |
| SCHEMBL6468997 | 0.89 | POLB (0.53) | POLBHTTAPEX1TDP1MAPT | |
| SCHEMBL6727442 | 0.89 | POLB (0.52) | POLBHTTAPEX1TDP1MAPT | |
| SCHEMBL6467307 | 0.89 | POLB (0.52) | POLBHTTAPEX1TDP1MAPT | |
| SCHEMBL19755947 | 0.89 | POLB (0.52) | POLBHTTAPEX1TDP1MAPT | |
| SCHEMBL17229438 | 0.88 | POLB (0.51) | POLBHTTAPEX1TDP1MAPT | |
| SCHEMBL495312 | 0.88 | NPC1 (0.53) | POLBMAPTNPC1LMNANFKB1 | |
| SCHEMBL22089873 | 0.87 | POLB (0.68) | POLBHTTAPEX1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11781070-B2 | Mesogen compounds | TRANSITIONS OPTICAL, LTD. (IE) | 2023-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11781070-B2 | Mesogen compounds | MDN1, LSG1, MNS1 | POLB 1404/4885HTT 1690/4885APEX1 2076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.