SCHEMBL6469176

SCHEMBL6469176

C=C[C@@]1(C)CC(=O)[C@H]2[C@](C)(O1)[C@@H](OC(C)=O)[C@@H](O)[C@H]1C(C)(C)CC[C@H](O)[C@@]12C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADCY1 Q08828 12/20 0.60
▸ MAPK1 P28482 5/20 0.60
▸ CYP3A4 P08684 4/20 0.60
▸ TSHR P16473 3/20 0.60
▸ SLC2A1 P11166 3/20 0.60
▸ NR1I2 O75469 2/20 0.60
▸ ADRA1A P35348 2/20 0.60
▸ KMT2A Q03164 2/20 0.60
▸ CYP2C19 P33261 2/20 0.60
▸ GMNN O75496 1/20 0.60
▸ BLM P54132 1/20 0.60
▸ PMP22 Q01453 1/20 0.60
▸ NPSR1 Q6W5P4 1/20 0.60
▸ CYP2D6 P10635 1/20 0.60
▸ NFKB1 P19838 1/20 0.60
▸ HIF1A Q16665 1/20 0.60
▸ CHRM2 P08172 1/20 0.60
▸ ABCB1 P08183 1/20 0.60
▸ HTR1A P08908 1/20 0.60
▸ ADRA2A P08913 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21779505 1.00 ADCY1 (0.60) ADCY1MAPK1CYP3A4TSHRSLC2A1
SCHEMBL11117898 1.00 ADCY1 (0.60) ADCY1MAPK1CYP3A4TSHRSLC2A1
SCHEMBL9870844 1.00 ADCY1 (0.60) ADCY1MAPK1CYP3A4TSHRSLC2A1
SCHEMBL10020759 1.00 ADCY1 (0.60) ADCY1MAPK1CYP3A4TSHRSLC2A1
SCHEMBL12028527 1.00 ADCY1 (0.60) ADCY1MAPK1CYP3A4TSHRSLC2A1
SCHEMBL13639992 1.00 ADCY1 (0.60) ADCY1MAPK1CYP3A4TSHRSLC2A1
SCHEMBL18601237 1.00 ADCY1 (0.60) ADCY1MAPK1CYP3A4TSHRSLC2A1
SCHEMBL31499204 0.92 ADCY1 (0.55) ADCY1MAPK1CYP3A4TSHRSLC2A1
SCHEMBL9591299 0.91 ADCY1 (0.55) ADCY1MAPK1CYP3A4TSHRSLC2A1
SCHEMBL10637035 0.91 ADCY1 (0.55) ADCY1MAPK1CYP3A4TSHRSLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0116713-A1 Novel labdane derivatives, process for the preparation thereof, and pharmaceutical compositions containing labdane derivatives SCHERING CORPORATION (US) 1984-08-29 — — EP claimed
WO-2025087947-A1 COSMETIC COMPOSITION FOR IMPROVING STRAND DENSITY OF THE HAIR PEIGNE, Catherine (FR) 2025-05-01 — — WO disclosed
EP-3687526-A1 A COMPOSITION FOR USE IN THE PREVENTION AND/OR TREATMENT OF GLAUCOMA Neilos S.r.l. (IT) 2020-08-05 — — EP disclosed
WO-2019064245-A1 A COMPOSITION FOR USE IN THE PREVENTION AND/OR TREATMENT OF GLAUCOMA Neilos S.r.l. (IT) 2019-04-04 — — WO disclosed
US-10240173-B2 Biosynthesis of forskolin and related compounds UNIVERSITY OF COPENHAGEN (DK) 2019-03-26 — — US disclosed
US-20190010527-A1 Biosynthesis of Forskolin and Related Compounds DANSTAR FERMENT AG (CH) 2019-01-10 — — US disclosed
US-10053717-B2 Biosynthesis of forskolin and related compounds UNIVERSITY OF COPENHAGEN (DK) 2018-08-21 — — US disclosed
US-20180112243-A1 BIOSYNTHESIS OF ACETYLATED 13R-MO AND RELATED COMPOUNDS EVOLVA SA (CH) 2018-04-26 — — US disclosed
EP-3283623-A1 BIOSYNTHESIS OF ACETYLATED 13R-MO AND RELATED COMPOUNDS Evolva SA (CH) 2018-02-21 — — EP disclosed
WO-2018015512-A1 BIOSYNTHESIS OF 13R-MANOYL OXIDE DERIVATIVES EVOLVA SA (CH) 2018-01-25 — — WO disclosed
US-4782082-A BRONCHODILATORS, ANTIHISTAMINES SCHERING CORPORATION (US) 1988-11-01 — — US disclosed
US-4740522-A Oxolabdanes useful as pharmaceuticals for reducing intraocular pressure HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1988-04-26 — — US disclosed
US-4734513-A Method of synthesizing forskolin from 9-deoxyforskolin HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1988-03-29 — — US disclosed
US-4734513-A Method of synthesizing forskolin from 9-deoxyforskolin HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1988-03-29 — — US disclosed
US-4734513-A Method of synthesizing forskolin from 9-deoxyforskolin HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1988-03-29 — — US disclosed
EP-0257631-A2 Oxolabdanes, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1988-03-02 — — EP disclosed
EP-0243646-A1 A process for the preparation of forskolin from 9-deoxy-forskolin and intermediates used therein HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1987-11-04 — — EP disclosed
EP-0243646-A1 A process for the preparation of forskolin from 9-deoxy-forskolin and intermediates used therein HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1987-11-04 — — EP disclosed
US-4517200-A Method for treating allergic reactions with forskolin SCHERING-PLOUGH CORPORATION (US) 1985-05-14 — — US disclosed
EP-0116713-A1 Novel labdane derivatives, process for the preparation thereof, and pharmaceutical compositions containing labdane derivatives SCHERING CORPORATION (US) 1984-08-29 — — EP disclosed
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