SCHEMBL6469183

SCHEMBL6469183

CCCCc1cccc(C(C)(C)Br)c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.45
LIPG Q9Y5X9 3/20 0.45
SKP2 Q13309 1/20 0.44
PPARG P37231 3/20 0.42
PPARA Q07869 3/20 0.42
KIF11 P52732 2/20 0.41
TAAR1 Q96RJ0 1/20 0.41
NPC1 O15118 1/20 0.40
HPGD P15428 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
XIAP P98170 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26030893 0.87 LPL (0.46) LPLLIPGSKP2PPARGPPARA
SCHEMBL6469287 0.84 LPL (0.44) LPLLIPGSKP2PPARGPPARA
SCHEMBL18242426 0.84 LPL (0.47) LPLLIPGSKP2PPARGPPARA
SCHEMBL3651924 0.84 LPL (0.44) LPLLIPGSKP2PPARGPPARA
SCHEMBL4538275 0.82 PPARA (0.44) LPLLIPGSKP2PPARGPPARA
SCHEMBL28423129 0.82 CNR2 (0.43) LPLLIPGPPARGPPARAKIF11
SCHEMBL256694 0.81 TAAR1 (0.62) TAAR1HTT
SCHEMBL28781933 0.81 LPL (0.45) LPLLIPGPPARGPPARAKIF11
SCHEMBL26369133 0.81 LPL (0.41) LPLLIPGSKP2PPARGPPARA
SCHEMBL6280362 0.80 LPL (0.54) LPLLIPGPPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1583780-A1 METHOD FOR CLAY EXFOLIATION, COMPOSITIONS THEREFORE, AND MODIFIED RUBBER CONTAIING SAME BRIDGESTONE CORPORATION (JP) 2005-10-12 EP disclosed
WO-2004058874-A1 METHOD FOR CLAY EXFOLIATION, COMPOSITIONS THEREFORE, AND MODIFIED RUBBER CONTAIING SAME BRIDGESTONE CORPORATION (JP) 2004-07-15 WO disclosed