Methane

Methane

SCHEMBL6469464

C.CCCCCC(C)C.OP(O)(O)=S.OP(O)(O)=S

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FDPS P14324 5/20 0.46
LAP3 P28838 2/20 0.43
OPRM1 P35372 1/20 0.42
SMPD1 P17405 3/20 0.41
LPAR2 Q9HBW0 3/20 0.40
LPAR3 Q9UBY5 3/20 0.40
LMNA P02545 2/20 0.40
CA1 P00915 2/20 0.40
SPHK1 Q9NYA1 1/20 0.40
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8812924 0.98 FDPS (0.48) FDPSLAP3OPRM1SMPD1LPAR2
SCHEMBL28666562 0.95 FDPS (0.50) FDPSLAP3SMPD1LPAR2LPAR3
SCHEMBL8812320 0.95 FDPS (0.50) FDPSLAP3SMPD1LPAR2LPAR3
SCHEMBL8412751 0.95 FDPS (0.46) FDPSLAP3OPRM1SMPD1LPAR2
Butane SCHEMBL3268713 0.93 FDPS (0.45) FDPSLAP3OPRM1SMPD1LPAR2
SCHEMBL8412695 0.93 FDPS (0.48) FDPSLAP3SMPD1LPAR2LPAR3
SCHEMBL29181951 0.93 SMPD1 (0.48) FDPSLAP3SMPD1LPAR2LPAR3
SCHEMBL8412548 0.93 FDPS (0.48) FDPSLAP3SMPD1LPAR2LPAR3
SCHEMBL28340115 0.93 FDPS (0.48) FDPSLAP3SMPD1LPAR2LPAR3
SCHEMBL8811717 0.90 FDPS (0.46) FDPSLAP3OPRM1LPAR2LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1137682-B1 DISPERSANT-VISCOSITY IMPROVERS FOR LUBRICATING OIL COMPOSITIONS LUBRIZOL CORP (US) 2005-03-02 EP disclosed
US-6472353-B1 Dispersant-viscosity improvers for lubricating oil compositions THE LUBRIZOL CORPORATION 2002-10-29 US disclosed
EP-1137682-A1 DISPERSANT-VISCOSITY IMPROVERS FOR LUBRICATING OIL COMPOSITIONS The Lubrizol Corporation (US) 2001-10-04 EP disclosed
WO-2001019882-A1 DISPERSANT-VISCOSITY IMPROVERS FOR LUBRICATING OIL COMPOSITIONS THE LUBRIZOL CORPORATION (US) 2001-03-22 WO disclosed