Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.49 |
| ▸ | EED | O75530 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29281499 | 0.81 | HRH3 (0.44) | HRH3HRH4ALDH1A1LMNAGAA | |
| SCHEMBL3158557 | 0.71 | HRH3 (0.58) | HRH3HRH4EEDKCNH2CHRNB2 | |
| SCHEMBL3161259 | 0.69 | HRH3 (0.51) | HRH3HRH4EEDKCNH2 | |
| SCHEMBL21359085 | 0.69 | HRH3 (0.51) | HRH3HRH4EED | |
| SCHEMBL21359086 | 0.69 | HRH3 (0.51) | HRH3HRH4EED | |
| SCHEMBL5188074 | 0.69 | EED (0.45) | HRH3HRH4EEDKCNH2CCNT1 | |
| SCHEMBL20281485 | 0.69 | HRH3 (0.48) | HRH3HRH4EEDKCNH2CHEK1 | |
| SCHEMBL13576643 | 0.68 | KCNH2 (0.53) | HRH3HRH4EEDALDH1A1KCNH2 | |
| SCHEMBL13576618 | 0.68 | KCNH2 (0.53) | HRH3HRH4EEDALDH1A1KCNH2 | |
| Hydrochloric Acid SCHEMBL21358856 | 0.68 | HRH3 (0.50) | HRH3HRH4EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1495002-A1 | BENZAMIDE DERIVATIVES USEFUL AS HISTONE DEACETYLASE INHIBITORS | Astrazeneca AB (SE) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087057-A1 | BENZAMIDE DERIVATIVES USEFUL AS HISTONE DEACETYLASE INHIBITORS | ASTRAZENECA AB (SE) | 2003-10-23 | — | — | WO | disclosed |