Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | EED | O75530 | 4/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13576618 | 1.00 | KCNH2 (0.53) | KCNH2EEDHTR3AHRH4HRH3 | |
| SCHEMBL4308696 | 0.89 | GBA1 (0.52) | KCNH2HTR3AHRH4HRH3ALDH1A1 | |
| SCHEMBL13576622 | 0.85 | EED (0.54) | KCNH2EEDHRH4HRH3P2RX7 | |
| SCHEMBL3466554 | 0.83 | EED (0.51) | EEDHRH4HRH3 | |
| SCHEMBL3158864 | 0.83 | EED (0.51) | EEDHRH4HRH3 | |
| SCHEMBL9748441 | 0.83 | EED (0.51) | EEDHRH4HRH3P2RX7ALDH1A1 | |
| SCHEMBL3467789 | 0.83 | EED (0.51) | EEDHRH4HRH3 | |
| SCHEMBL14609341 | 0.83 | EED (0.55) | KCNH2EEDHRH4HRH3P2RX7 | |
| SCHEMBL8547993 | 0.82 | EED (0.61) | EEDHRH4HRH3 | |
| SCHEMBL3473180 | 0.82 | EED (0.61) | EEDHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009148291-A2 | 3- OR 4-SUBSTITUTED PIPERIDINE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2009-12-10 | — | — | WO | disclosed |