Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | KDM5A | P29375 | 1/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | OGG1 | O15527 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28169553 | 0.98 | MPO (0.61) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL2678949 | 0.87 | MPO (0.80) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL343630 | 0.87 | MPO (0.80) | MPOCYP3A4BLMKDM5AGFER | |
| Methylglyoxal SCHEMBL2952275 | 0.87 | MAPT (0.50) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL19607546 | 0.86 | MPO (0.64) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL28188923 | 0.85 | MPO (0.76) | MPOCYP3A4BLMKDM5AGFER | |
| Benzoic Acid Hydrazide SCHEMBL11735247 | 0.85 | CYP3A4 (0.58) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL9787399 | 0.84 | HDAC6 (0.56) | OGG1CA1CA2CA9 | |
| SCHEMBL8292215 | 0.84 | MPO (0.61) | MPOCYP3A4BLMKDM5AGFER | |
| SCHEMBL5924140 | 0.82 | MAPT (0.46) | MPOCYP3A4BLMKDM5AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023161296-A1 | CONJUGATION METHOD INVOLVING A TRANSGLUTAMINASE AT THE FC REGION COMPRISING A TRIMMED N-GLYCAN | ADC THERAPEUTICS SA (CH) | 2023-08-31 | — | — | WO | disclosed |
| CN-111228212-A | Drug-loaded injectable implantation in-situ hydrogel | 中国人民解放军军事科学院军事医学研究院 | 2020-06-05 | — | — | CN | disclosed |
| WO-2005016949-A2 | SIALIC ACID DERIVATIVES | LIPOXEN TECHNOLOGIES LIMITED (GB) | 2005-02-24 | — | — | WO | disclosed |