Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469479 | 0.89 | MAOA (0.59) | MAOATOP2AAPEX1MAPTMEN1 | |
| SCHEMBL61277 | 0.84 | AKR1C3 (0.54) | MAOATOP2AMAPTMEN1KMT2A | |
| SCHEMBL29440787 | 0.84 | AKR1C3 (0.54) | MAOATOP2AMAPTMEN1KMT2A | |
| SCHEMBL29440785 | 0.84 | AKR1C3 (0.54) | MAOATOP2AMAPTMEN1KMT2A | |
| SCHEMBL6469873 | 0.81 | NPC1 (0.52) | MAOATOP2AMAPTMEN1KMT2A | |
| SCHEMBL5776241 | 0.79 | ELANE (0.53) | AHRAPEX1MAPTMEN1KMT2A | |
| SCHEMBL6762328 | 0.78 | MAOA (0.48) | MAOAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5842306 | 0.74 | KDM4E (0.57) | MAOATOP2AMAPTMEN1KMT2A | |
| SCHEMBL313075 | 0.74 | KDM4E (0.58) | MAOAMAPTMEN1KMT2AHPGD | |
| SCHEMBL16203168 | 0.73 | KDM6B (0.67) | MAOAMAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050235428-A1 | Use of metal complex compounds as oxidation catalysts | CIBA SPECIALTY CHEMICALS CORP. | 2005-10-27 | — | — | US | disclosed |
| EP-1456216-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | Ciba SC Holding AG (CH) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053986-A1 | USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-07-03 | — | — | WO | disclosed |