Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.42 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366439 | 0.81 | TLR9 (0.50) | TLR9EPHX2SOAT2SOAT1FAAH | |
| SCHEMBL8366438 | 0.81 | TLR9 (0.50) | TLR9EPHX2SOAT2SOAT1FAAH | |
| SCHEMBL6901746 | 0.80 | EPHX2 (0.51) | TLR9EPHX2SOAT2SOAT1FAAH | |
| SCHEMBL6901744 | 0.80 | EPHX2 (0.51) | TLR9EPHX2SOAT2SOAT1FAAH | |
| SCHEMBL7011863 | 0.79 | TLR9 (0.52) | TLR9TBXA2REPHX2ALDH1A1CYP1A2 | |
| SCHEMBL7011858 | 0.79 | TLR9 (0.52) | TLR9TBXA2REPHX2ALDH1A1CYP1A2 | |
| SCHEMBL11555215 | 0.76 | TLR9 (0.44) | TLR9ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11555212 | 0.76 | TLR9 (0.44) | TLR9ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11558255 | 0.75 | TLR9 (0.55) | TLR9TBXA2RALDH1A1HSD11B1CYP1A2 | |
| SCHEMBL11558258 | 0.75 | TLR9 (0.55) | TLR9TBXA2RALDH1A1HSD11B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019181-A1 | MIGRASTATIN ANALOG CELL MIGRATION INHIBITORS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2005-03-03 | — | — | WO | disclosed |