Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7011858 | 1.00 | TLR9 (0.52) | TLR9TDP1EPHX2PSIP1CTSK | |
| SCHEMBL8366439 | 0.95 | TLR9 (0.50) | TLR9TDP1EPHX2PSIP1CTSK | |
| SCHEMBL8366438 | 0.95 | TLR9 (0.50) | TLR9TDP1EPHX2PSIP1CTSK | |
| SCHEMBL6901744 | 0.93 | EPHX2 (0.51) | TLR9TDP1EPHX2PSIP1PTPN1 | |
| SCHEMBL6901746 | 0.93 | EPHX2 (0.51) | TLR9TDP1EPHX2PSIP1PTPN1 | |
| SCHEMBL7795086 | 0.88 | TLR9 (0.61) | TLR9TDP1EPHX2PSIP1ALDH1A1 | |
| SCHEMBL6465522 | 0.81 | TLR9 (0.59) | TLR9TDP1PSIP1CTSKALDH1A1 | |
| SCHEMBL6465524 | 0.81 | TLR9 (0.59) | TLR9TDP1PSIP1CTSKALDH1A1 | |
| SCHEMBL6469846 | 0.79 | TLR9 (0.44) | TLR9EPHX2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL16168390 | 0.78 | CTSK (0.41) | TLR9EPHX2CTSKPTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358186-A1 | LAULIMALIDE DERIVATIVES | Kosan Biosciences, Inc. (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002064589-A1 | LAULIMALIDE DERIVATIVES | KOSAN BIOSCIENCES, INC. (US) | 2002-08-22 | — | — | WO | disclosed |