Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8779513 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL8779559 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL8779549 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL5087462 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL7752437 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL8171329 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6901790 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL3149072 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7643713 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL565820 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10618987-B2 | Modified catalyst supports | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2020-04-14 | — | — | US | claimed |
| US-20190161565-A1 | Modified Catalyst Supports | TOTAL RES & TECHNOLOGY FELUY (BE) | 2019-05-30 | — | — | US | claimed |
| EP-2513163-A1 | PROCESS FOR THE PREPARATION OF A PARTICULATE BIMODAL POLYETHYLENE PRODUCT | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2012-10-24 | — | — | EP | claimed |
| US-20120245307-A1 | PROCESS FOR THE PREPARATION OF A PARTICULATE BIMODAL POLYETHYLENE PRODUCT | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2012-09-27 | — | — | US | claimed |
| US-10618987-B2 | Modified catalyst supports | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2020-04-14 | — | — | US | disclosed |
| US-20190161565-A1 | Modified Catalyst Supports | TOTAL RES & TECHNOLOGY FELUY (BE) | 2019-05-30 | — | — | US | disclosed |
| EP-2465879-B1 | Bridged metallocene compound for olefin polymerization and method of polymerizing olefin using the same | MITSUI CHEMICALS INC (JP) | 2019-04-24 | — | — | EP | disclosed |
| US-10233268-B2 | Modified catalyst supports | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2019-03-19 | — | — | US | disclosed |
| EP-2542594-B1 | MODIFIED CATALYST SUPPORTS | TOTAL RES & TECHNOLOGY FELUY (BE) | 2018-02-21 | — | — | EP | disclosed |
| EP-2751149-B1 | POLYETHYLENE WITH LOW CATALYTIC RESIDUES | TOTAL RES & TECHNOLOGY FELUY (BE) | 2017-05-31 | — | — | EP | disclosed |
| US-9475893-B2 | Modified catalyst supports | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2016-10-25 | — | — | US | disclosed |
| EP-2588501-B1 | MODIFIED CATALYST SUPPORTS | TOTAL RES & TECHNOLOGY FELUY (BE) | 2016-03-23 | — | — | EP | disclosed |
| US-20120245307-A1 | PROCESS FOR THE PREPARATION OF A PARTICULATE BIMODAL POLYETHYLENE PRODUCT | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2012-09-27 | — | — | US | disclosed |
| WO-2012020145-A1 | MODIFIED CATALYST SUPPORTS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2012-02-16 | — | — | WO | disclosed |
| EP-0881232-B1 | Catalyst for olefin polymerization and process for the production of an olefin polymer | TOSOH CORP (JP) | 2005-03-16 | — | — | EP | disclosed |
| US-6777367-B2 | MIXING ALUMOXANE COCATALYST PARTICLES WITH A SUPPORT IN AN AROMATIC HYDROCARBON SOLVENT; CONTACTING WITH A DISPERSION OF METALLOCENE IN AN AROMATIC HYDROCARBON SOLVENT; WASHING WITH A PARAFFIN; DISPERSING IN VISCOUS MINERAL OIL | FINA TECHNOLOGY, INC. | 2004-08-17 | — | — | US | disclosed |
| EP-0942006-B1 | Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst | TOSOH CORP (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-20020137623-A1 | Method for the preparation of metallocene catalysts | FINA TECHNOLOGY, INC. | 2002-09-26 | — | — | US | disclosed |
| EP-1231225-A1 | Method for the preparation of metallocene catalysts | FINA TECHNOLOGY, INC. (US) | 2002-08-14 | — | — | EP | disclosed |
| US-6110858-A | AN OLEFIN POLYMERIZATION CATALYST CONSISTS OF A TRANSITION METAL COMPOUND, A MODIFIED CLAY COMPOUND CONTAINING CLAY MINERAL AND AN AMINE COMPOUND AND AN ORGANOALUMINUM COMPOUND | TOSOH CORPORATION (JP) | 2000-08-29 | — | — | US | disclosed |