SCHEMBL6470130

SCHEMBL6470130

CCCCP(=O)(C(=O)c1c(CC)cc(CC)cc1CC)C(=O)c1c(CC)cc(CC)cc1CC

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.34
KDM4E B2RXH2 1/20 0.33
CETP P11597 4/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
GPR84 Q9NQS5 1/20 0.31
GABBR2 O75899 1/20 0.31
GABRR1 P24046 1/20 0.31
GABBR1 Q9UBS5 1/20 0.31
POLB P06746 1/20 0.30
MTNR1A P48039 1/20 0.30
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
HSPA5 P11021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6470043 0.95 CETP (0.38) KDM4ECETPMEN1GAAKMT2A
SCHEMBL6467881 0.94 CETP (0.40) CETP
SCHEMBL6470386 0.94 CETP (0.40) CETP
SCHEMBL6466115 0.94 CETP (0.40) CETP
SCHEMBL6470378 0.90 MEN1 (0.34) MEN1GAAKMT2APOLBRXRA
SCHEMBL6470195 0.85 TSHR (0.45) TSHRCETPMEN1KMT2APOLB
SCHEMBL6470341 0.84 PTPN1 (0.38) TSHRCETPGPR84
SCHEMBL6465884 0.82 MEN1 (0.36) MEN1GAAKMT2APOLBRXRA
SCHEMBL6469741 0.80 CETP (0.42) TSHRCETPMEN1KMT2A
SCHEMBL6470028 0.79 CETP (0.44) CETPMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050096406-A1 Reactive diluents and alkyd resin coating compositions PRETOT ROGER (CH) 2005-05-05 US disclosed
US-5534559-A UNSATURATED POLYESTERS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed