SCHEMBL6470195

SCHEMBL6470195

CCCCP(=O)(C(=O)c1c(CC)cccc1CC)C(=O)c1c(CC)cccc1CC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
BID P55957 3/20 0.40
MCL1 Q07820 3/20 0.40
BCL2L1 Q07817 2/20 0.40
BAK1 Q16611 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
PPARA Q07869 2/20 0.40
PPARG P37231 1/20 0.40
EP300 Q09472 1/20 0.40
KAT2A Q92830 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT5 Q92993 1/20 0.40
SAE1 Q9UBE0 1/20 0.40
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6469741 0.95 CETP (0.42) TSHRBIDMCL1BCL2L1BAK1
SCHEMBL6469815 0.93 CETP (0.44) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL6470028 0.93 CETP (0.44) BIDMCL1BCL2L1BAK1KAT8
SCHEMBL5994741 0.92 TSHR (0.40) TSHRBIDMCL1BCL2L1BAK1
SCHEMBL5994659 0.89 PPARA (0.51) TSHRPPARASMN1; SMN2ALDH1A1
SCHEMBL5995012 0.89 TSHR (0.38) TSHRBIDMCL1BCL2L1BAK1
SCHEMBL5995560 0.85 TSHR (0.35) TSHRBIDMCL1BCL2L1BAK1
SCHEMBL6470130 0.85 TSHR (0.34) TSHRMEN1KMT2APOLBCETP
SCHEMBL5994436 0.84 PPARA (0.41) TSHRPPARASMN1; SMN2MEN1ALDH1A1
SCHEMBL6467225 0.83 TSHR (0.41) TSHRSMN1; SMN2MEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050096406-A1 Reactive diluents and alkyd resin coating compositions PRETOT ROGER (CH) 2005-05-05 US disclosed
US-5534559-A UNSATURATED POLYESTERS CIBA-GEIGY CORPORATION (US) 1996-07-09 US disclosed