Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395459 | 1.00 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL444872 | 0.93 | PTGS2 (0.69) | PTGS2PTGS1 | |
| Water SCHEMBL27918427 | 0.90 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL7677302 | 0.87 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL10300269 | 0.87 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL7938593 | 0.86 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL6724517 | 0.86 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL215130 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6724238 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8974060 | 0.82 | PTGS2 (0.64) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406696-A1 | USE OF COMPOSITIONS COMPRISING CYCLOOXYGENASE-2 SELECTIVE INHIBITORS IN COMBINATION WITH RADIATION FOR INHIBITION OR PREVENTION OF CARDIOVASCULAR DISEASE | Pharmacia Corporation (US) | 2004-04-14 | — | — | EP | claimed |
| WO-2002096516-A1 | USE OF COMPOSITIONS COMPRISING CYCLOOXYGENASE-2 SELECTIVE INHIBITORS IN COMBINATION WITH RADIATION FOR INHIBITION OR PREVENTION OF CARDIOVASCULAR DISEASE | PHARMACIA CORPORATION (US) | 2002-12-05 | — | — | WO | claimed |
| EP-1536863-A1 | USE OF CYCLOOXYGENASE-2 SELECTIVE INHIBITORS AND THROMBOLYTIC AGENTS FOR THE TREATMENT OR PREVENTION OF A VASO-OCCLUSIVE EVENT | Pharmacia Corporation (US) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004004833-A1 | USE OF CYCLOOXYGENASE-2 SELECTIVE INHIBITORS AND THROMBOLYTIC AGENTS FOR THE TREATMENT OR PREVENTION OF A VASO-OCCLUSIVE EVENT | PHARMACIA CORPORATION (US) | 2004-01-15 | — | — | WO | disclosed |