Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 15/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10919184 | 0.78 | ALDH1A1 (0.50) | TLR8MAPTBTKKDM4E | |
| SCHEMBL24851768 | 0.76 | KMT2A (0.59) | TLR8MAPTBTKKDM4E | |
| SCHEMBL30162418 | 0.76 | TLR8 (0.45) | TLR8MAPTBTKKDM4E | |
| SCHEMBL24852090 | 0.76 | ALDH1A1 (0.45) | TLR8MAPTBTKKDM4E | |
| SCHEMBL30162608 | 0.76 | KMT2A (0.59) | TLR8MAPTBTKKDM4E | |
| SCHEMBL24853011 | 0.76 | TLR8 (0.45) | TLR8MAPTBTKKDM4E | |
| SCHEMBL13197354 | 0.74 | CYP1A2 (0.47) | TLR8MAPTBTK | |
| SCHEMBL30162784 | 0.74 | ALDH1A1 (0.43) | TLR8MAPTBTKKDM4E | |
| SCHEMBL6575516 | 0.74 | BCL2L11 (0.46) | TLR8MAPTBTKKDM4E | |
| Acridine SCHEMBL27894463 | 0.73 | MAPT (0.68) | TLR8MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007143-A2 | USE OF MAKROLIDES AND KETOLIDES FOR THE TREATMENT OF TUBERCULOSIS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2005-01-27 | — | — | WO | disclosed |