⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4895507 | 0.79 | — | — | |
| SCHEMBL8313074 | 0.75 | — | — | |
| SCHEMBL133762 | 0.72 | — | — | |
| SCHEMBL10490809 | 0.69 | CYP3A4 (0.39) | — | |
| SCHEMBL6255517 | 0.68 | — | — | |
| SCHEMBL4438400 | 0.68 | — | — | |
| SCHEMBL1028751 | 0.68 | — | — | |
| SCHEMBL4871847 | 0.68 | — | — | |
| SCHEMBL4716628 | 0.68 | — | — | |
| SCHEMBL1142633 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10865180-B2 | Process for the preparation of l-Norepinephrine bitartrate monohydrate having high enantiomeric purity | HARMAN FINOCHEM LIMITED (IN) | 2020-12-15 | — | — | US | disclosed |
| US-20200048185-A1 | PROCESS FOR THE PREPARATION OF l-NOREPINEPHRINE BITARTRATE MONOHYDRATE HAVING HIGH ENANTIOMERIC PURITY | HARMAN FINOCHEM LIMITED | 2020-02-13 | — | — | US | disclosed |
| WO-2005092359-A1 | EXTRACT OF MUCUNA SPECIES AND THE USE THEREOF AS ANTI-PARKINSONS’S DISEASE PHARMACEUTICAL | SCOTT & WHITE MEMORIAL HOSPITAL (US) | 2005-10-06 | — | — | WO | disclosed |