⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1035723 | 0.79 | — | — | |
| SCHEMBL3725914 | 0.75 | — | — | |
| SCHEMBL133762 | 0.72 | — | — | |
| SCHEMBL169196 | 0.69 | — | — | |
| SCHEMBL4438400 | 0.68 | — | — | |
| SCHEMBL128265 | 0.68 | — | — | |
| SCHEMBL6255517 | 0.68 | — | — | |
| SCHEMBL6470192 | 0.68 | — | — | |
| SCHEMBL27983420 | 0.68 | — | — | |
| SCHEMBL4871847 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019075-B9 | BETA 2-ADRENERGIC RECEPTOR AGONISTS | THERAVANCE INC (US) | 2006-08-16 | — | — | EP | claimed |
| EP-1019075-B1 | BETA 2-ADRENERGIC RECEPTOR AGONISTS | THERAVANCE INC (US) | 2005-08-24 | — | — | EP | claimed |
| US-20040186080-A1 | Beta 2-adrenergic receptor agonists | THERAVANCE BIOPHARMA R&D IP, LLC | 2004-09-23 | — | — | US | claimed |
| US-6713651-B1 | RESPIRATORY AND NERVOUS SYSTEM DISORDERS, PREMATURE LABOR | THERAVANCE, INC. | 2004-03-30 | — | — | US | claimed |
| US-6683115-B2 | A MULTIBINDING COMPOUND CONTAINING A LINKER AND A LIGAND, USEFUL FOR TREATING RESPIRATORY DISEASES SUCH AS ASTHMA AND CHRONIC BRONCHITIS, AND ARE ALSO USEFUL IN THE TREATMENT OF NERVOUS SYSTEM INJURY AND PREMATURE LABOR | THERAVANCE, INC. | 2004-01-27 | — | — | US | claimed |
| US-20030087307-A1 | Beta2-adrenergic receptor agonists | ADVANCED MEDICINE, INC. | 2003-05-08 | — | — | US | claimed |
| US-6541669-B1 | Multibinding amine compounds which are beta 2 adrenergic receptor agonists useful in treatment and prevention of respiratory diseases such as asthma, bronchitis | THERAVANCE, INC. | 2003-04-01 | — | — | US | claimed |
| JP-2002517459-A | — | — | 2002-06-18 | — | — | JP | claimed |
| JP-2002517457-A | — | — | 2002-06-18 | — | — | JP | claimed |
| JP-2002517460-A | — | — | 2002-06-18 | — | — | JP | claimed |
| EP-1019075-A1 | $g(b)2-ADRENERGIC RECEPTOR AGONISTS | Advanced Medicine, Inc. (US) | 2000-07-19 | — | — | EP | claimed |
| EP-1019360-A1 | $g(b)2-ADRENERGIC RECEPTOR AGONISTS | Advanced Medicine, Inc. (US) | 2000-07-19 | — | — | EP | claimed |
| EP-1019360-A4 | $g(b)2-ADRENERGIC RECEPTOR AGONISTS | ADVANCED MEDICINE INC (US) | 2000-07-19 | — | — | EP | claimed |
| WO-1999064035-A9 | β2-ADRENERGIC RECEPTOR AGONISTS | ADVANCED MEDICINE INC (US) | 2000-07-06 | — | — | WO | claimed |
| WO-1999064034-A9 | β2-ADRENERGIC RECEPTOR AGONISTS | ADVANCED MEDICINE INC (US) | 2000-06-29 | — | — | WO | claimed |
| EP-1003540-A1 | $g(b)2-ADRENERGIC RECEPTOR AGONISTS | Advanced Medicine, Inc. (US) | 2000-05-31 | — | — | EP | claimed |
| WO-1999064031-A9 | β2-ADRENERGIC RECEPTOR AGONISTS | ADVANCED MEDICINE INC (US) | 2000-05-04 | — | — | WO | claimed |
| WO-1999064035-A1 | β2-ADRENERGIC RECEPTOR AGONISTS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | claimed |
| WO-1999064031-A1 | β2-ADRENERGIC RECEPTOR AGONISTS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | claimed |
| WO-1999064034-A1 | β2-ADRENERGIC RECEPTOR AGONISTS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | claimed |